HAMARI’S CONTRIBUTION TO THE ASYMMETRIC SYNTHESIS OF TAILOR-MADE AMINO ACIDS(Review)

• Date: 2024
• Author Affiliations: Jianlin Han — Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China; Hong Liu — State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; Jiang Wang — State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; Alicja Wzorek — Institute of Chemistry, Jan Kochanowski University in Kielce, Uniwersytecka 7, 25-406 Kielce, Poland; Alexander Sorochinsky — Department of Fine Organic Synthesis, V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, The National Academy of Sciences of Ukraine, 1 Murmanska str., Kyiv 02094, Ukraine; Karel Klika — Molecular Structure Analysis, German Cancer Research Center (DKFZ), ImNeuenheimer Feld 280, 69120 Heidelberg, Germany; Taizo Ono — National Institute of Advanced Industrial Science and Technology, 463-8560, Nagoya, Japan; Hiroki Moriwaki — Hamari Chemical Ltd., Osaka, Japan; Tatsunori Sato — Hamari Chemical Ltd., Osaka, Japan; Izawa Kunisuke — Hamari Chemical Ltd., Osaka, Japan; Hiroyuki Konno — Department of Chemistry and Biological Engineering, Graduate School of Science and Engineering, Yamagata University, 992-8510 Yonezawa, Yamagata, Japan; Vadim Soloshonok — University of Basque Country
• Keywords: keywords
• Main Authors: Han, Jianlin, Liu, Hong, Wang, Jiang, Wzorek, Alicja, Sorochinsky, Alexander, Klika, Karel, Ono, Taizo, Moriwaki, Hiroki, Sato, Tatsunori, Kunisuke , Izawa, Konno, Hiroyuki, Soloshonok, Vadim
• Format: Article
• Language: English
• Published: V.I.Vernadsky Institute of General and Inorganic Chemistry 2024
• Online Access: https://ucj.org.ua/index.php/journal/article/view/693
• Journal Title: Ukrainian Chemistry Journal

This article reviews the development of the asymmetric synthesis of tailor-made amino acids conducted at Hamari Chemicals during the 10-year period 2013–2022.The discussion is based on strategies such as direct chiral modification of unprotected amino acids via intermediate formation of Ni(II) compl...