COMPOSITES OF CALCIUM PHOSPHATE AND ZIRCONIUM DIOXIDE AS BIOCOMPATIBLE COATINGS OF METAL IMPLANTS
Modern surgery usage of metal implants demands the new requirements for their quality and special properties. In particular, when treating damaged bones, problems of implant integration into tissues often arise (due to allergic reactions, inflammatory processes etc.). This issue is especially actua...
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| Дата: | 2024 |
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| Автори: | , , , , , , , |
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
V.I.Vernadsky Institute of General and Inorganic Chemistry
2024
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| Онлайн доступ: | https://ucj.org.ua/index.php/journal/article/view/697 |
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| Назва журналу: | Ukrainian Chemistry Journal |
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oai:ojs2.1444248.nisspano.web.hosting-test.net:article-6972025-04-08T13:54:06Z COMPOSITES OF CALCIUM PHOSPHATE AND ZIRCONIUM DIOXIDE AS BIOCOMPATIBLE COATINGS OF METAL IMPLANTS Zatovsky, Іgor Strutynska, Nataliia Nikolenko, Ilariia Temchenko, Volodymyr Ogorodnyk, Ivan Lehenchuk, Oleksii Odynets, Ievgen Slobodyanik, Mykola hydroxyapatite (HA), zirconia (ZrO2), gas detonation deposition (GDD) method, implants, biocompatible coating. Modern surgery usage of metal implants demands the new requirements for their quality and special properties. In particular, when treating damaged bones, problems of implant integration into tissues often arise (due to allergic reactions, inflammatory processes etc.). This issue is especially actual due to the war in Ukraine, which cause a huge number of wounds and injuries. The most promising way to overcome this problem is to create biocompatible and stable coatings on the surface of metal implants. The reported investigations deal with the preparation of biocompatible coatings on the surface of model metal implants which is based on a combination of hydroxyapatite and zirconium dioxide (doped with 5% wt. yttrium oxide) using the gas detonation deposition (GDD) method. The initial complex-substituted hydroxyapatites containing sodium ions and carbonate groups were obtained by precipitation from aqueous solutions (systems Na+ - Ca2+ - CO32- - NO3- - PO43-), and their fine dispersed mixture with ZrO2 to create coatings was carried out mechanically. The investigations of a structure and a composition of the coatings was carried out using powder X-ray diffracion, differential thermal analysis, scanning electron microscopy and IR spectroscopy. Preliminary medical and biological tests on animals (rats) revealed that the obtained results can be used in the creation of new generation medical implants for surgery, orthopedics and dentistry. Partial resorption of hydroxyapatite on the surface of the implants was revealed, which contributes to the formation of the interface between the implant and the bone and the formation of the primary cellular matrix. Among the main advantages of using the GDD method for deposition of controlled structure and composition coatings on metal substrate it should be noted both the relatively low cost and the possibility of creating a coating with high adhesion. This indicates significant prospects for the outlined approach for practical application in the therapy of damaged bones. V.I.Vernadsky Institute of General and Inorganic Chemistry 2024-12-27 Article Article Inorganic Chemistry Неорганическая химия Неорганічна хімія application/pdf https://ucj.org.ua/index.php/journal/article/view/697 10.33609/2708-129X.90.11.2024.7-16 Ukrainian Chemistry Journal; Vol. 90 No. 11 (2024): Ukrainian Chemistry Journal; 7-16 Украинский химический журнал; Том 90 № 11 (2024): Ukrainian Chemistry Journal; 7-16 Український хімічний журнал; Том 90 № 11 (2024): Ukrainian Chemistry Journal; 7-16 2708-129X 2708-1281 en https://ucj.org.ua/index.php/journal/article/view/697/347 |
| institution |
Ukrainian Chemistry Journal |
| baseUrl_str |
|
| datestamp_date |
2025-04-08T13:54:06Z |
| collection |
OJS |
| language |
English |
| topic_facet |
hydroxyapatite (HA) zirconia (ZrO2) gas detonation deposition (GDD) method implants biocompatible coating. |
| format |
Article |
| author |
Zatovsky, Іgor Strutynska, Nataliia Nikolenko, Ilariia Temchenko, Volodymyr Ogorodnyk, Ivan Lehenchuk, Oleksii Odynets, Ievgen Slobodyanik, Mykola |
| spellingShingle |
Zatovsky, Іgor Strutynska, Nataliia Nikolenko, Ilariia Temchenko, Volodymyr Ogorodnyk, Ivan Lehenchuk, Oleksii Odynets, Ievgen Slobodyanik, Mykola COMPOSITES OF CALCIUM PHOSPHATE AND ZIRCONIUM DIOXIDE AS BIOCOMPATIBLE COATINGS OF METAL IMPLANTS |
| author_facet |
Zatovsky, Іgor Strutynska, Nataliia Nikolenko, Ilariia Temchenko, Volodymyr Ogorodnyk, Ivan Lehenchuk, Oleksii Odynets, Ievgen Slobodyanik, Mykola |
| author_sort |
Zatovsky, Іgor |
| title |
COMPOSITES OF CALCIUM PHOSPHATE AND ZIRCONIUM DIOXIDE AS BIOCOMPATIBLE COATINGS OF METAL IMPLANTS |
| title_short |
COMPOSITES OF CALCIUM PHOSPHATE AND ZIRCONIUM DIOXIDE AS BIOCOMPATIBLE COATINGS OF METAL IMPLANTS |
| title_full |
COMPOSITES OF CALCIUM PHOSPHATE AND ZIRCONIUM DIOXIDE AS BIOCOMPATIBLE COATINGS OF METAL IMPLANTS |
| title_fullStr |
COMPOSITES OF CALCIUM PHOSPHATE AND ZIRCONIUM DIOXIDE AS BIOCOMPATIBLE COATINGS OF METAL IMPLANTS |
| title_full_unstemmed |
COMPOSITES OF CALCIUM PHOSPHATE AND ZIRCONIUM DIOXIDE AS BIOCOMPATIBLE COATINGS OF METAL IMPLANTS |
| title_sort |
composites of calcium phosphate and zirconium dioxide as biocompatible coatings of metal implants |
| description |
Modern surgery usage of metal implants demands the new requirements for their quality and special properties. In particular, when treating damaged bones, problems of implant integration into tissues often arise (due to allergic reactions, inflammatory processes etc.). This issue is especially actual due to the war in Ukraine, which cause a huge number of wounds and injuries. The most promising way to overcome this problem is to create biocompatible and stable coatings on the surface of metal implants. The reported investigations deal with the preparation of biocompatible coatings on the surface of model metal implants which is based on a combination of hydroxyapatite and zirconium dioxide (doped with 5% wt. yttrium oxide) using the gas detonation deposition (GDD) method. The initial complex-substituted hydroxyapatites containing sodium ions and carbonate groups were obtained by precipitation from aqueous solutions (systems Na+ - Ca2+ - CO32- - NO3- - PO43-), and their fine dispersed mixture with ZrO2 to create coatings was carried out mechanically. The investigations of a structure and a composition of the coatings was carried out using powder X-ray diffracion, differential thermal analysis, scanning electron microscopy and IR spectroscopy. Preliminary medical and biological tests on animals (rats) revealed that the obtained results can be used in the creation of new generation medical implants for surgery, orthopedics and dentistry. Partial resorption of hydroxyapatite on the surface of the implants was revealed, which contributes to the formation of the interface between the implant and the bone and the formation of the primary cellular matrix. Among the main advantages of using the GDD method for deposition of controlled structure and composition coatings on metal substrate it should be noted both the relatively low cost and the possibility of creating a coating with high adhesion. This indicates significant prospects for the outlined approach for practical application in the therapy of damaged bones. |
| publisher |
V.I.Vernadsky Institute of General and Inorganic Chemistry |
| publishDate |
2024 |
| url |
https://ucj.org.ua/index.php/journal/article/view/697 |
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2025-09-24T17:43:58Z |
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2025-09-24T17:43:58Z |
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