Синтез α-флуорованих α-циклопентил-заміщених будівельних блоків

• Опубліковано в: Ukrainica Bioorganica Acta
• Дата: 2026
• Том: 21
• Випуск: 1
• Сторінки: 127-130
• ISSN: 1814-9766
• Автори та афіліації: Bohdan V. Bobovskyi — Enamine Ltd. (www.enamine.net), Kyiv, Ukraine; V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the NAS of Ukraine, Kyiv, Ukraine; Bohdan S. Sosunovych — Enamine Ltd. (www.enamine.net), Kyiv, Ukraine; Bohdan V. Vashchenko — Enamine Ltd. (www.enamine.net), Kyiv, Ukraine; Taras Shevchenko National University of Kyiv, Kyiv, Ukraine; Enamine Scientific Research Institute (SRI), Kyiv, Ukraine; Anton A. Klipkov — Enamine Ltd. (www.enamine.net), Kyiv, Ukraine; V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the NAS of Ukraine, Kyiv, Ukraine; Illia O. Feskov — Enamine Ltd. (www.enamine.net), Kyiv, Ukraine; V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the NAS of Ukraine, Kyiv, Ukraine; Denys V. Bylina — Enamine Ltd. (www.enamine.net), Kyiv, Ukraine; Taras Shevchenko National University of Kyiv, Kyiv, Ukraine; Oleksandr Pokholenko — Enamine Ltd. (www.enamine.net), Kyiv, Ukraine; Taras Shevchenko National University of Kyiv, Kyiv, Ukraine — ORCID: 0009-0004-5140-8783; Igor I. Gerus — V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the NAS of Ukraine, Kyiv, Ukraine; Oleksandr O. Grygorenko — Enamine Ltd. (www.enamine.net), Kyiv, Ukraine; V.P. Kukhar Institute of Bioorganic Chemistry and Penal University ; Enamine Scientific Research Institute (SRI), Kyiv, Ukraine
• Автори: Bobovskyi, Bohdan V., Sosunovych, Bohdan S., Vashchenko, Bohdan V., Klipkov, Anton A., Feskov, Illia O., Bylina, Denys V., Pokholenko, Oleksandr, Gerus, Igor I., Grygorenko, Oleksandr O.
• Формат: Стаття
• Мова: Англійська
• Опубліковано: V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine 2026
• Теми: циклопентан; флуор; будівельні блоки
• Онлайн доступ: https://bioorganica.com.ua/index.php/journal/article/view/148
• Назва журналу: Ukrainica Bioorganica Acta

The synthesis of mono- and difluorinated -cyclopentyl-substituted carboxylates was accomplished using complementary synthetic approaches. The obtained esters were transformed into corresponding carboxylic acids, alcohols, and amines. The effect of fluorination on physicochemical properties was eval...