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Багатограмовий синтез β-флуорованих насичених гетероциклічних метанамінів
An efficient multigram synthesis of β-fluorinated saturated heterocyclic methanamines - promising building blocks for drug discovery, starting from the corresponding saturated heterocyclic ketones is described. The method includes Wittig olefination, bromofluorination, nucleophilic substitution with...
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Main Authors: | , |
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Format: | Article |
Language: | English |
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V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine
2023
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Online Access: | https://bioorganica.com.ua/index.php/journal/article/view/73 |
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