Багатограмовий синтез β-флуорованих насичених гетероциклічних метанамінів

An efficient multigram synthesis of β-fluorinated saturated heterocyclic methanamines - promising building blocks for drug discovery, starting from the corresponding saturated heterocyclic ketones is described. The method includes Wittig olefination, bromofluorination, nucleophilic substitution with...

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Bibliographic Details
Date:2023
Main Authors: Semeno, Volodymyr V., Melnykov, Kostiantyn P.
Format: Article
Language:English
Published: V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine 2023
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Online Access:https://bioorganica.com.ua/index.php/journal/article/view/73
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Journal Title:Ukrainica Bioorganica Acta

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Ukrainica Bioorganica Acta