Синтез нового 1-бензоїлгексагідро-2Н-піроло[3,4-d]піримідин-2,4(3Н)-діону

We report an efficient [3+2] cycloaddition involving non-stabilized electron-rich azomethine ylides and 1,3-dibenzoyl-pyrimidine-2,4(1H,3H)-dione. The 1,3-dipole was prepared in situ under TFA catalysis, and we obtained the product in good yield and with full control of the regioselectivity

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Bibliographic Details
Date:2025
Main Authors: Melnychuk, Pavlo V., Shablykin, Oleg V.
Format: Article
Language:English
Published: V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine 2025
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Online Access:https://bioorganica.com.ua/index.php/journal/article/view/99
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Journal Title:Ukrainica Bioorganica Acta

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Ukrainica Bioorganica Acta