Antiproliferative and apoptotic effects of anti-human HB-EGF neutralizing polyclonal antibodies in vitro

• Datum: 2023
• Hauptverfasser: Siromolot, A.A., Krynina, O.I., Kolybo, D.V., Komisarenko, S.V.
• Format: Artikel
• Sprache: Englisch
• Veröffentlicht: PH Akademperiodyka 2023
• Schlagworte: antibodies.; cancer treatment.; HB-EGF; mitogenic activation; receptors
• Online Zugang: https://exp-oncology.com.ua/index.php/Exp/article/view/2020-1-8
• Назва журналу: Experimental Oncology

Summary. Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a member of the epidermal growth factor family and has a variety of physiological and pathophysiological functions. Also, HB-EGF plays a pivotal role in progression of different tumors. So, HB-EGF seems to be a target mo...