Aberrant expression of placental-like alkaline phosphatase in chronic myeloid leukemia cells in vitro and its modulation by vitamin E

• Date: 2023
• Main Authors: Shvachko, L.P., Zavelevich, M.P., Gluzman, D.F., Telegeev, G.D.
• Format: Article
• Language: English
• Published: PH Akademperiodyka 2023
• Subjects: alkaline phosphatase; chronic myeloid leukemia; differentiation; vitamin E.
• Online Access: https://exp-oncology.com.ua/index.php/Exp/article/view/2020-1-10
• Journal Title: Experimental Oncology

Summary. Placental-like alkaline phosphatase (PLAP) is expressed by many tumors and can be detected in sera of patients with various cancers. Its aberrant expression has been considered to be potentially useful as tumor marker. However, the biological background of the role of this aberrant alkaline...