Proteomics of transforming growth factor β1 (TGF β1) signaling in 184A1 human breast epithelial cells suggests the involvement of casein kinase 2α in TGF β1-dependent p53 phosphorylation at Ser392

• Datum: 2023
• Hauptverfasser: Woksepp, H., Saini, R.K.R., Zakharchenko, O., Gautier, A., Souchelnytskyi, N., Souchelnytskyi, S.
• Format: Artikel
• Sprache: English
• Veröffentlicht: PH Akademperiodyka 2023
• Schlagworte: CK2α; p53; proteomics; transforming growth factor β
• Online Zugang: https://exp-oncology.com.ua/index.php/Exp/article/view/2019-4-6
• Назва журналу: Experimental Oncology

Summary. Aim: Transforming growth factor β1 (TGF β1) is a potent regulator of breast tumorigenesis. It inhibits proliferation of carcinoma cells, but the strength of its inhibitory action varies for cells from benigh, non-metastatic or metastatic tumors. The aim of this work was to...