Proteomics of transforming growth factor β1 (TGF β1) signaling in 184A1 human breast epithelial cells suggests the involvement of casein kinase 2α in TGF β1-dependent p53 phosphorylation at Ser392

• Date: 2023
• Main Authors: Woksepp, H., Saini, R.K.R., Zakharchenko, O., Gautier, A., Souchelnytskyi, N., Souchelnytskyi, S.
• Format: Article
• Language: English
• Published: PH Akademperiodyka 2023
• Subjects: CK2α; p53; proteomics; transforming growth factor β
• Online Access: https://exp-oncology.com.ua/index.php/Exp/article/view/2019-4-6
• Journal Title: Experimental Oncology

Summary. Aim: Transforming growth factor β1 (TGF β1) is a potent regulator of breast tumorigenesis. It inhibits proliferation of carcinoma cells, but the strength of its inhibitory action varies for cells from benigh, non-metastatic or metastatic tumors. The aim of this work was to...