Vitamin Е activates expression of С/EBP alpha transcription factor and G-CSF receptor in leukemic K562 cells

Vitamin Е activates expression of С/EBP alpha transcription factor and G-CSF receptor in leukemic K562 cells

Summary. Background: Chronic myeloid leukemia (CML) is a clonal hematopoietic stem cell disorder associated with the activity of BCR-ABL fusion oncogene. Tyrosine kinase inhibitors are the current treatment of CML, but secondary mutations finally contribute to therapy resistance and blast crisis of...

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Bibliographic Details
Date:2018
Main Authors: Shvachko, L.P., Zavelevich, M.P., Gluzman, D.F., Kravchuk, I.V., Telegeev, G.D.
Format: Article
Language:English
Published: PH Akademperiodyka 2018
Subjects:
C/EBP alpha transcription factor
chronic myeloid leukemia
G-CSFR
granulocytic differentiation
vitamin E.
Online Access:https://exp-oncology.com.ua/index.php/Exp/article/view/2018-4-13
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Journal Title:Experimental Oncology

Institution

Experimental Oncology

Internet

https://exp-oncology.com.ua/index.php/Exp/article/view/2018-4-13

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