Діагностика і хірургічне лікуванн я гастроінтестинальних стромальних пухлин шлунку із застосуванням мініінвазивних технологій

• Date: 2025
• Main Authors: Moiseienko, A., Dibrova, V., Melnyk, O.
• Format: Article
• Language: English
• Published: PH Akademperiodyka 2025
• Subjects: ГІСП шлунку; біопсія; лапароскопічна резекція шлунка; інтраопераційна фіброгастродуоденоскопія; імуногістохімія
• Online Access: https://exp-oncology.com.ua/index.php/Exp/article/view/544
• Journal Title: Experimental Oncology

Background. Gastrointestinal stromal tumors of the stomach (GIST) are relatively rare, and in 65% of cases, their primary localization is the stomach wall. Considering that the incidence of GIST is 1.2 cases per 10⁵ people per year, not all aspects of the treatment and diagnostic tactics are sufficiently studied. The aim of the study was to examine the possibilities of modern methods of preoperative verification of GIST of the stomach and the effectiveness of their surgical treatment using minimally invasive technologies. Materials and Methods. We analyzed the results of surgical treatment using minimally invasive technologies for 24 GIST patients with tumor localization in the stomach wall treated in the clinic of the Bogomolets National Medical University in 2017—2025. Histological and immunohistochemical analyses of the biopsy and surgical materials were performed. Results. The choice of a method for performing gastric resection depended on the localization and size of the tumor, and the type of its growth. Of 17 (70.8%) patients with the exophytic type of GIST growth, 13 (54.2%) patients had significant difficulties with verification of the tumor in the gastric wall during laparoscopic revision. Conclusion. The results of the study are consistent with international data and emphasize the need for morphological typing and the use of immunohistochemical markers for accurate diagnosis, risk stratification, and selection of further treatment tactics for patients with GIST of the stomach.