ВИПАДОК РІДКІСНОЇ МУТАЦІЇ CASR, ПОВ’ЯЗАНОЇ З HER2-ПОЗИТИВНИМ РАКОМ ГРУДНОЇ ЗАЛОЗИ

• Date: 2026
• Main Authors: Kitsera, N., Shparyk, Ya., Duda, I., Mylyan, Yu., Kunta, N.
• Format: Article
• Language: English
• Published: PH Akademperiodyka 2026
• Online Access: https://exp-oncology.com.ua/index.php/Exp/article/view/620
• Journal Title: Experimental Oncology

Although highly penetrant genes such as BRCA1, BRCA2, TP53, PALB2, CHEK2, and ATM are well known in hereditary breast cancer, genes with low penetrance may also contribute to the disease risk. The CASR (Calcium-Sensing Receptor) gene, located on chromosome 3q13.3–q21, encodes a G-protein-coupled rec...