Надання надчутливим до температури переходам у біологічних макромолекулах змісту ентропійно-керованих процесів розгортання
The two-configuration approximation based on the thermodynamic approach to describing conformational transitions in physiologically significant biological macromolecules, e.g. some specific RNA molecules known as RNA-thermometers, is used to derive the consistent equation for determining the thermod...
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| Date: | 2026 |
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| Main Authors: | , |
| Format: | Article |
| Language: | English Ukrainian |
| Published: |
Publishing house "Academperiodika"
2026
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| Subjects: | |
| Online Access: | https://ujp.bitp.kiev.ua/index.php/ujp/article/view/2023755 |
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| Journal Title: | Ukrainian Journal of Physics |
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Ukrainian Journal of Physics| Summary: | The two-configuration approximation based on the thermodynamic approach to describing conformational transitions in physiologically significant biological macromolecules, e.g. some specific RNA molecules known as RNA-thermometers, is used to derive the consistent equation for determining the thermodynamic probability of the entropy-driven unfolded process which is extra-sensitive to ambient temperature. We show that with the given accuracy of the involved parameters this equation coincides with the equation obtained using the microscopic approach. We then compare the derived equation with experimental data and finally discuss and conclude the results obtained. |
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| DOI: | 10.15407/ujpe71.5.419 |