Diffusion approximation of the Wright-Fisher model of population genetics: Single-locus two alleles
We investigate an autoregressive diffusion approximation method applied to the Wright-Fisher model in population genetics by considering a Markov chain with Bernoulli distributed independent variables. The use of an autoregressive diffusion method and an averaged allelic frequency process lead to an...
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| Datum: | 2000 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | Ukrainisch Englisch |
| Veröffentlicht: |
Institute of Mathematics, NAS of Ukraine
2000
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| Online Zugang: | https://umj.imath.kiev.ua/index.php/umj/article/view/4423 |
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| Назва журналу: | Ukrains’kyi Matematychnyi Zhurnal |
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Ukrains’kyi Matematychnyi Zhurnal| Zusammenfassung: | We investigate an autoregressive diffusion approximation method applied to the Wright-Fisher model in population genetics by considering a Markov chain with Bernoulli distributed independent variables. The use of an autoregressive diffusion method and an averaged allelic frequency process lead to an Orn-stein-Uhlenbeck diffusion process with discrete time. The normalized averaged frequency process possesses independent allele frequency indicators with constant conditional variance at equilibrium. In a monoecious diploid population of size N with r generations, we consider the time to equilibrium of averaged allele frequency in a single-locus two allele pure sampling model. |
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