Correlations between molecular parameters of guest substances and their effect on model lipid membranes

Correlations between molecular parameters of guest substances and their effect on model lipid membranes

Effect of guests molecules on phase transitions of model lipid membranes was studied by differential scanning calorimetry. Membranotropic action of guest molecules was estimated from the shift of "gel - liquid crystal" phase transition temperature of lipid membranes. Relationships between...

Повний опис

Збережено в:
Бібліографічні деталі
Дата:2016
Автори: Sadchenko, A.O., Vashchenko, O.V., Kasian, N.A., Budianska, L.V., Lisetski, L.N.
Формат: Стаття
Мова:English
Опубліковано: НТК «Інститут монокристалів» НАН України 2016
Назва видання:Functional Materials
Теми:
Characterization and properties
Онлайн доступ:http://dspace.nbuv.gov.ua/handle/123456789/120623
Теги: Додати тег
Немає тегів, Будьте першим, хто поставить тег для цього запису!
Назва журналу:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Цитувати:Correlations between molecular parameters of guest substances and their effect on model lipid membranes / A.O. Sadchenko, O.V. Vashchenko, N.A. Kasian, L.V. Budianska, L.N. Lisetski // Functional Materials. — 2016. — Т. 23, № 2. — С. 230-235. — Бібліогр.: 31 назв. — англ.

Репозитарії

Digital Library of Periodicals of National Academy of Sciences of Ukraine
id irk-123456789-120623
record_format dspace
spelling irk-123456789-1206232017-06-13T03:06:14Z Correlations between molecular parameters of guest substances and their effect on model lipid membranes Sadchenko, A.O. Vashchenko, O.V. Kasian, N.A. Budianska, L.V. Lisetski, L.N. Characterization and properties Effect of guests molecules on phase transitions of model lipid membranes was studied by differential scanning calorimetry. Membranotropic action of guest molecules was estimated from the shift of "gel - liquid crystal" phase transition temperature of lipid membranes. Relationships between membranotropic action and molecular parameters of guest molecules (volume, surface area, dipole moment, anisometry, lipophilicity coefficient, fraction of the polar area, etc.) were examined. For most of the lipophilic substances studied a high linear correlations between membranotropic action and lipophilicity coefficient (r = 0.86), as well as fraction of polar molecular area (r = -0.83) were established. For hydrophilic substances such correlations were not found. For groups of substances with similar chemical nature (glycerol derivatives, ammonium compounds), high linear correlations (r > 0.8) were established between membranotropic action and such molecular parameters as surface area, volume, dipole moment. 2016 Article Correlations between molecular parameters of guest substances and their effect on model lipid membranes / A.O. Sadchenko, O.V. Vashchenko, N.A. Kasian, L.V. Budianska, L.N. Lisetski // Functional Materials. — 2016. — Т. 23, № 2. — С. 230-235. — Бібліогр.: 31 назв. — англ. 1027-5495 DOI: dx.doi.org/10.15407/fm23.02.230 http://dspace.nbuv.gov.ua/handle/123456789/120623 en Functional Materials НТК «Інститут монокристалів» НАН України
institution Digital Library of Periodicals of National Academy of Sciences of Ukraine
collection DSpace DC
language English
topic Characterization and properties
Characterization and properties
spellingShingle Characterization and properties
Characterization and properties
Sadchenko, A.O.
Vashchenko, O.V.
Kasian, N.A.
Budianska, L.V.
Lisetski, L.N.
Correlations between molecular parameters of guest substances and their effect on model lipid membranes
Functional Materials
description Effect of guests molecules on phase transitions of model lipid membranes was studied by differential scanning calorimetry. Membranotropic action of guest molecules was estimated from the shift of "gel - liquid crystal" phase transition temperature of lipid membranes. Relationships between membranotropic action and molecular parameters of guest molecules (volume, surface area, dipole moment, anisometry, lipophilicity coefficient, fraction of the polar area, etc.) were examined. For most of the lipophilic substances studied a high linear correlations between membranotropic action and lipophilicity coefficient (r = 0.86), as well as fraction of polar molecular area (r = -0.83) were established. For hydrophilic substances such correlations were not found. For groups of substances with similar chemical nature (glycerol derivatives, ammonium compounds), high linear correlations (r > 0.8) were established between membranotropic action and such molecular parameters as surface area, volume, dipole moment.
format Article
author Sadchenko, A.O.
Vashchenko, O.V.
Kasian, N.A.
Budianska, L.V.
Lisetski, L.N.
author_facet Sadchenko, A.O.
Vashchenko, O.V.
Kasian, N.A.
Budianska, L.V.
Lisetski, L.N.
author_sort Sadchenko, A.O.
title Correlations between molecular parameters of guest substances and their effect on model lipid membranes
title_short Correlations between molecular parameters of guest substances and their effect on model lipid membranes
title_full Correlations between molecular parameters of guest substances and their effect on model lipid membranes
title_fullStr Correlations between molecular parameters of guest substances and their effect on model lipid membranes
title_full_unstemmed Correlations between molecular parameters of guest substances and their effect on model lipid membranes
title_sort correlations between molecular parameters of guest substances and their effect on model lipid membranes
publisher НТК «Інститут монокристалів» НАН України
publishDate 2016
topic_facet Characterization and properties
url http://dspace.nbuv.gov.ua/handle/123456789/120623
citation_txt Correlations between molecular parameters of guest substances and their effect on model lipid membranes / A.O. Sadchenko, O.V. Vashchenko, N.A. Kasian, L.V. Budianska, L.N. Lisetski // Functional Materials. — 2016. — Т. 23, № 2. — С. 230-235. — Бібліогр.: 31 назв. — англ.
series Functional Materials
work_keys_str_mv AT sadchenkoao correlationsbetweenmolecularparametersofguestsubstancesandtheireffectonmodellipidmembranes
AT vashchenkoov correlationsbetweenmolecularparametersofguestsubstancesandtheireffectonmodellipidmembranes
AT kasianna correlationsbetweenmolecularparametersofguestsubstancesandtheireffectonmodellipidmembranes
AT budianskalv correlationsbetweenmolecularparametersofguestsubstancesandtheireffectonmodellipidmembranes
AT lisetskiln correlationsbetweenmolecularparametersofguestsubstancesandtheireffectonmodellipidmembranes
first_indexed 2023-10-18T20:37:30Z
last_indexed 2023-10-18T20:37:30Z
_version_ 1796150687278563328

Схожі ресурси